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Answer: USE
USE is a New York Times Crossword puzzle answer that we have spotted 315 times.
Meaning
Use, in the context of manipulate, means to employ or apply something for a specific purpose or to one's advantage.
Note: The provided meaning of the answer is for the latest New York Times crossword puzzle clue: Deplete, with "up". Explanations are generated by AI and may be inaccurate.
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Recent usage in crossword puzzles
- New York Times - May 13, 2024
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